What to Expect After Your Injection
Kenalog-40 is a long-acting corticosteroid that reduces inflammation at the site of injection. It typically begins working within 24–72 hours, with noticeable reduction in swelling, redness, and discomfort over several days to a week.
You may experience:
- Mild soreness or tenderness at the injection site (for 1–2 days)
 
- A slight dimple or indentation at the injection site (temporary)
 
- Thinning or lightening of the skin in the treated area (may occur in sensitive skin)
 
- Gradual shrinking of the lesion (e.g., cyst or keloid)
 
Aftercare Instructions
DO:
- Keep the treated area clean and dry
 
- Avoid touching or picking at the injection site
 
- Apply a gentle, fragrance-free moisturizer if the area becomes dry
 
- Resume your normal skincare routine after 24 hours, unless otherwise advised
 
- Use SPF daily if the area is exposed to sunlight
 
AVOID for 24–48 Hours:
- Applying harsh skincare ingredients (retinol, acids, or peels) directly on or near the site
 
- Massaging, rubbing, or scratching the treated area
 
- Heat exposure (saunas, steam rooms, intense workouts)
 
- Facial treatments, microneedling, or chemical peels on the area
 
Common Side Effects (Mild and Temporary)
- Mild pain, tenderness, or redness at injection site
 
- Temporary skin thinning or discoloration
 
- A small indentation or flattening of the skin
 
- Lightening of the skin (hypopigmentation), especially in deeper skin tones
 
These effects typically resolve on their own within several weeks to months.
Rare Side Effects
Although rare, monitor for:
- Persistent or worsening pain
 
- Infection at the site (increased redness, swelling, pus)
 
- Allergic reaction (itching, rash, or swelling away from the injection site)
 
- Atrophy or permanent dimpling of the skin
 
When to Contact SKINLAB
Please contact us immediately if you experience:
- Signs of infection: warmth, pain, pus, or fever
 
- Severe or worsening redness, swelling, or skin breakdown
 
- Unusual pigmentation changes or spreading discoloration
 
- Any side effects that feel unusual or concerning